 | | Jon Menke |
Jon R. Menke Graduate Research Assistant University of Minnesota Department of Plant Pathology USDA-ARS Cereal Disease Laboratory 1551 Lindig Street St. Paul, MN 55108 Email: menk0001@umn.edu Graduate Advisor: Dr. H. Corby Kistler | 2006-present | PhD Student, Plant Pathology Department of Plant Pathology University of Minnesota | | 1997 | B.S. Microbiology College of Biological Sciences University of Minnesota |
Research Focus
Cereals infected with Fusarium graminearum (F. graminearum), the causative agent of Fusarium Head Blight (FHB), are reduced in seed quality and yield and tainted with Type B trichothecenes, making them unsuitable for consumption. Acute symptoms of tricothecene exposure in humans include gastric and intestinal lesions, CNS toxicity, and suppression of immunity and reproductive function. My research is focused on Type B trichothecene toxin production by F. graminaerum and the mechanisms by which the fungus ameliorates trichothecene toxicity. Additionally, I am researching differential gene expression of F. graminearum in wheat and rice using Affymetrix GeneChip arrays to identify genes associated with decreased Type B trichothecene toxin production in F. graminearum infested rice relative to F. graminearum infested wheat. Professional Experience
| 2004-2005 | Research Associate Life Sciences Research Division Bio-Rad Laboratories, Hercules, CA
| | 2001-2004 | Research Associate R&D Department of MJ Bioworks. MJ Bioworks, South San Francisco, CA | | 1999-2001 | Research Associate J. Gladstone Institute of Cardiovascular Disease. J. David Gladstone Institutes, San Francisco, CA | | 1998-1999 | Research Associate Subclone Sequencing Division of the Human Genome Center. Lawrence Berkeley National Laboratory, Berkeley, CA | | 1997-1998 | Research Associate Clinical Development Division of Process Sciences. Bayer, Inc., Berkeley, CA | Publications
B. E. Lockhart, J. Menke, G. Dahal, and N. E. Olszewski. Characterization and genomic analysis of tobacco vein clearing virus, a plant pararetrovirus that is transmitted vertically and related to sequences integrated in the host genome. Journal of General Virology 2000 81:1579-1585. |