There are well over one million species of filamentous fungi but only a tiny fraction of those cause plant diseases on agricultural crops. What makes pathogenic fungi different from those that do not cause disease or are beneficial to plants? Research in my lab uses genomic approaches to discover the mechanisms by which fungi cause disease in plants. Most of our effort focuses on Fusarium graminearum, the head blight pathogen of wheat and barley, and Fusarium oxysporum which causes wilt diseases on a variety of crops.
Learn about new research from the Kistler Lab which expands ways to control head blight and vomitoxin accumulation by the discovery of new sources of plant resistance that could be replicated in agricultural crops. Read more >>
Kistler Lab Update
In the summer of 2016, the Kistler lab was visited by Ailisa Blum, a Ph.D. student from the University of Queensland, Brisbane Australia. Ms. Blum works on Fusarium diseases of wheat in the laboratory of Donald Gardiner at CSIRO, Brisbane. During her visit she conducted microscopic studies of the fungus Fusarium graminearum and localized fluorescently tagged enzymes involved in the synthesis of the mycotoxin deoxynivalenol (DON). Using super-resolution microscopy she was able to visualize and characterize previously unknown affinities between two enzymes in the DON biosynthetic pathway. This work will be presented at the 29th Fungal Genetics Conference sponsored by the Genetic Society of America, on March 14, 2017 in Pacific Grove, California along with Kistler lab co-authors Marike Boenisch and Karen Broz. The title of their presentation will be: “Nanoscale clustering of the cytosolic enzyme trichodiene synthase to a trichothecene biosynthetic enzyme complex at the endoplasmic reticulum resolved by superresolution microscopy and FRET.” Kistler lab graduate student Sean O’Mara also will be attending the meeting and presenting a poster entitled “Trichothecene mycotoxin transport in the phytopathogen Fusarium graminearum” with co-authors Yanhong Dong and Karen Broz. More details of the meeting and complete abstracts may be found at http://www.genetics-gsa.org/fungal/2017/.
The Kistler Lab does not currently have graduate student positions available
Department of Plant Pathology | 495 Borlaug Hall 1991 Upper Buford Circle | St. Paul, MN 55108 (612) 625-8200 | Fax: (612) 625-9728 | email@example.com